Jasmin Coulombe-Huntington
Faculty Lecturer
Ph.D., Bioinformatics, Boston University
M.Sc., Human Genetics, McGill University
B.Sc., Biochemistry, McGill University
Machine learning, data mining, large-scale data integration and web resources
Genome-wide CRISPR screens
Bioinformatics algorithm design
Systems biology
Network-based modelling
Comparative genomics and proteomics
Short linear interaction motif prediction
Mapping and predicting gene functions and protein interactions
Epigenetics, transcriptional regulation and alternative splicing
Omics-based diagnostics and prevention
Plasma DNA sequencing
Mass spectrometry-based proteomics and metabolomics
Drug repurposing
Influence of diet and environment on health
Bertomeu T*, Coulombe-Huntington J*, Chatr-aryamontri A, Bourdages K, Coyaud E, Raught B, Xia Y, Tyers M. 2018. A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome. Molecular Cell Biology
Coulombe-Huntington J, Xia Y. 2017. Network Centrality Analysis in Fungi Reveals Complex Regulation of Lost and Gained Genes. PLoS ONE
Yang X*, Coulombe-Huntington J*, Kang S*, Sheynkman GM, Hao T, ...,Xia Y, Vidal M.. 2016. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell
Sahni N*, Yi S*, Taipale M*, Fuxman Bass JI*, Coulombe-Huntington J*, ..., Roth FP, Xia Y, Walhout AJM, Lindquist S , Vidal M. 2015. Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders. Cell
Coulombe-Huntington J, Xia Y. (2012), Regulatory Network Structure as a Dominant Determinant of Transcription Factor Evolutionary Rate. PLoS Computational Biology
Coulombe-Huntington J, Lam K, Dias C, Majewski J. 2009. Fine-Scale Variation and Genetic Determinants of Alternative Splicing across Individuals. PLoS Genetics.
Coulombe-Huntington J, Majewski J. 2007. Intron loss and gain in Drosophila. Molecular Biology and Evolution
Coulombe-Huntington J, Majewski J. 2007. Characterization of intron loss events in mammals. Genome Research *equal contribution