Dr. Philipp Voigt, Assistant Professor Welcome Trust Centre for Cell Biology (WTCOB)

Dr. Philipp Voigt

Assistant Professor

Welcome Trust Centre for Cell Biology (WTCOB)

University of Edinburgh

Seminar Title: “Histone Methylation Crosstalk at Developmental Genes”

Host Lab: Lisa Munter

Seminar:                  

Wednesday, August 2, 2017

12:00pm 

Room 1345

McIntyre Medical Sciences Building

http://www.wcb.ed.ac.uk/research/philipp-voigt

The genetic information  of eukaryotic organisms is packaged into chromatin, a complex assembly of DNA, RNA, and proteins. The basic unit of chromatin is the nucleosome, which is formed by DNA wrapping around a histone octamer. Histones not only constitute the structural backbone of chromatin but also provide ample opportunity for regulating  gene expression. They undergo a host  of posttranslational modifications, which are thought to impact transcription either by directly modulating chromatin structure or by recruiting effector proteins. The overarching goal of research in our lab is to determine the mechanistic intricacies of histone modifications. Moreover, we aim to understand how different systems of chromatin modifiers interact to regulate and fine-tune gene expression.