Event

CCVC Seminar: Dr. Huw M. L. Davies - Collaborative Approach for C-H Functionalization

Tuesday, October 13, 2015 13:00to14:30
Maass Chemistry Building Room 10, 801 rue Sherbrooke Ouest, Montreal, QC, H3A 0B8, CA

The development of practical methods for site selective C-H functionalization is of intense current interest. This presentation will describe a collaborative approach towards achieving new C-H functionalization strategies and our recent advances in the C-H insertion chemistry of donor/acceptor-substituted carbenoids. A series of chiral dirhodium catalysts have been developed for this chemistry and they are capable of controlling which C-H bond is functionalized.  The application of these new synthetic strategies to the synthesis of natural products and pharmaceutical targets will be described.m

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