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Darcy Wagner

Academic title(s): 

Professor, Department of Biomedical Engineering

Professor, Department of Medicine, Division of Experimental Medicine

Canada Excellence Research Chair in Lung Regenerative Medicine

Faculty, Meakins-Christie Laboratories (Meakins)

Scientist, Translational Research in Respiratory Diseases Program (RESP) at the Research Institute of the McGill University Health Centre (RI-MUHC)

Principal Investigator, McGill Regenerative Medicine Network (MRM Network)

Darcy Wagner
Link(s): 
Lab Website
Contact Information
Address: 

Research Institute of the McGill University Health Centre

1001 Décarie Blvd., Block E, Montreal, QC, CANADA H4A 3J1

Email address: 
darcy.wagner [at] mcgill.ca
Department: 
Biomedical Engineering
Experimental Medicine
Areas of expertise: 

Our lab focuses on how the extracellular environment directs stem cell behavior for endogenous and exogenous lung tissue regeneration. We use a multidisciplinary approach using advances in materials science (polymer design and synthesis), manufacturing (e.g. 3D bioprinting), and endogenous and iPSC-derived lung stem cells to construct these new models.

The main areas of interest of the lab are:

  • Design and use of biologic (acellular) and synthetic scaffolds in diverse manufacturing approaches to bioengineer new lung tissue for transplantation.

  • Understand the role of the extracellular matrix in directing lung stem cell behaviour in vivo and ex vivo during regeneration (normal and pathologic)

  • Build and validate new models of human lung tissue and chronic lung disease to reduce animal usage and for use as drug discovery and therapeutic screening platforms

Keywords: bioengineering, lung regeneration, biomaterials, stem cells, bioprinting, microfluidics, light sheet fluorescence microscopy, image analysis

Research areas: 
Biomaterials and Tissue Engineering
Biomolecular and Cellular Engineering
Imaging and Microscopy
Bioinformatics and Computational Biology
Area(s): 
Biomaterials
Tissue Engineering
Lab-on-a-chip
Porous Biomaterials
Green Chemistry
Image Processing
Scaffolds
Regenerative Medicine
Next-generation Sequencing (NGS)
Bioinformatics
3-D and 4-D Imaging
Stem Cell Therapy
Microencapsulation
3D Printing
Tissue Regeneration
Light Sheet Fluorescence Microscopy (LSFM)
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