BIC Feindel Brain and Mind Seminar Series: Revisiting the Large-Scale Functional Processing Hierarchy in the Human Brain: Development, Architecture, and Information Flow
The Feindel Brain and Mind Seminar Series will advance the vision of Dr. William Feindel (1918–2014), Former Director of the Neuro (1972–1984), to constantly bridge the clinical and research realms. The talks will highlight the latest advances and discoveries in neuropsychology, cognitive neuroscience, and neuroimaging.
Speakers will include scientists from across The Neuro, as well as colleagues and collaborators locally and from around the world. The series is intended to provide a virtual forum for scientists and trainees to continue to foster interdisciplinary exchanges on the mechanisms, diagnosis and treatment of brain and cognitive disorders.
To attend in person, register here
To watch via Vimeo, click here
Seok-Jun Hong
Associate Professor, Department of Biomedical Engineering, Sungkyunkwan University, South Korea
Host: boris.bernhardt [at] mcgill.ca (Boris Bernhardt)
Abstract: The principle of information flow across distributed brain networks is paramount in neuroscience. Among the macroscale architectures for this neural dynamic, large-scale cortical hierarchy is the most principal basis, providing a scaffold for nearly all cognitive functions related to perception, action and social processes. In this talk, I will first introduce our recent findings from imaging, transcriptomics and developmental network simulation to show how this hierarchical axis could gradually emerge from interaction with the thalamus during brain development. Next, I will showcase our new framework leveraging integrated effective connectivity and information flow mapping to reveal a directed functional hierarchy and demonstrate a sensorimotor-heteromodal-paralimbic processing stream in human brain and how this architecture could reorganize according to brain state changes. Finally, I will close my presentation by briefly summarizing my perspective on the potential embedding of the internal-external organization in the brain and their functional role in maintaining the survival of a living agent.
