Research Assistant (Early Drug Discovery Unit under Dr. Thomas Durcan)

Primary duties:
The candidate selected will work in the Neuro’s Early Drug Discovery Unit under the supervision of Dr. Thomas Durcan focused on neuronal organoid and image analysis projects. Will be responsible for generating and characterizing neuronal organoid models derived from patient-derived induced pluripotent stem cells (iPSCs) as part of these projects. Tasks for these projects will include maintaining panels of iPSCs, following in house methods to generate 3D neuronal organoids across multiple projects, organoid fixations perfusions, tissue clearing, organoid staining, image acquisition and processing. Additional duties will include developing new software packages with support from other team members for analysis of the image datasets from the organoid sections and the intact 3D organoid, obtained through both confocal and light sheet microscopy.

The selected candidate will also assist with other organizational tasks within the lab, including overseeing inventories of cells and reagents needed for the different projects, for working with different members of the team in coordinating regular meetings. The selected candidate will also collect and interpret results from these research experiments that will be included in future publications. Along with these duties, will also be responsible for preparing reports and updating laboratory procedures on a regular basis, along with other related duties as assigned.