• Regular cytology screening (pap or smear test) is still the most commonly used HPV screening method, and can prevent cancers up to age 75 years, although benefits decline with age
  • For the newly introduced HPV DNA test, which offers a higher degree of accuracy, women aged 55 who have a negative test were predicted to be at low risk of cervical cancer 
Classified as: Gerald Bronfman Department of Oncology, HPV
Published on: 2 Nov 2018

Source: Cell Metabolism

New research suggests that higher-level brain functions have a major role in losing weight. In a study among 24 participants at a weight-loss clinic, those who achieved greatest success in terms of weight loss demonstrated more activity in the brain regions of the lateral prefrontal cortex associated with self-control. The results of the study were published in Cell Metabolism on October 18.

Classified as: Department of Neurology & Neurosurgery, Montreal Neurological Institute and Hospital (The Neuro)
Published on: 18 Oct 2018

Brain cancer begins in stem cells, targeting them may prevent tumour growth

Researchers at the Montreal Neurological Institute and Hospital (The Neuro) have found an exciting new way of treating brain cancer.

Late stage brain cancer cells are heterogeneous — they differ down to the molecular level. This makes developing treatments at this stage difficult, because a drug that may be effective against one cell may not be effective against another.

Classified as: brain cancer, glioblastoma, brain tumour, Kevin Petrecca
Published on: 15 Oct 2018

Researchers discover additional targets for existing drugs used to treat a specific melanoma

 

A set of targeted cancer drugs, known as BRAF and MEK inhibitors, have proven to be beneficial for some metastatic melanoma patients whose tumours include a specific mutation in the BRAF gene, known as V600E. A recent study conducted in the lab of Dr. Peter Siegel at McGill University’s Goodman Cancer Research Centre suggests that these same drugs may prove beneficial for a broader range of cancer patients.

Classified as: Goodman Cancer Research Centre, Rosalind and Morris Cancer Research Centre
Published on: 4 Oct 2018

The Consortium for Industrial Research and Innovation in Medical Technologies, MEDTEQ, and the Healthy Brains for Healthy Lives (HBHL) initiative of McGill University are pleased to announce a joint agreement that will harmonize the process of developing research and innovation projects related to medical technologies.

Classified as: neuroscience, medical research, innovation
Category:
Published on: 3 Oct 2018

Carriers at higher risk of developing neurodegenerative disease

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital (The Neuro) has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson’s disease (PD), dementia with Lewy-Bodies (DLB) and multiple system atrophy (MSA).

Classified as: MNI, genetics, Parkinson's disease, Healthy Brains for Healthy Lives, multiple system atrophy, Lewy-Bodies, PD, Ziv Gan-Or
Published on: 1 Oct 2018

To all members of the Faculty of Medicine,

Further to last week’s update on the McIntyre Medical Sciences Building, during which we confirmed the opening of the 5th and 6th floor amphitheatres and 2nd floor classrooms, we are pleased to report that the following additional areas will be opened as follows:

Published on: 10 Sep 2018

To all members of the Faculty of Medicine,

With the new academic year set to begin in earnest, I am pleased to report a great deal of progress has been made with respect to remediation efforts at the McIntyre Building following the July 13 fire. I take this opportunity to thank the University’s Project Review team who have taken over the reins from the Emergency Operations Committee and who continue their meticulous work to minimize disruptions to our community.

Please take note of the following updates:

Building Access:

Published on: 31 Aug 2018

When it comes to weight gain, the problem may be mostly in our heads, and our genes

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.

Classified as: alain dagher, Uku Vainik, obesity, brain volume, MRI, human connectome project, PNAS
Published on: 28 Aug 2018

To all members of the Faculty of Medicine,

Published on: 10 Aug 2018

One of the tightest bottlenecks in vascular tissue engineering is the lack of strength and elasticity of engineered vascular wall models caused by limited elastic fiber deposition. In this study, collagen gel-based scaffolds were cellularised with vascular smooth muscle cells (SMCs) and supplemented with human plasma fibronectin (FN), a known master organizer of several extracellular matrix (ECM) fiber systems.

Classified as: department anatomy cell biology
Published on: 9 Aug 2018

Fibronectin is a protein that exists in vertebrates in two distinct forms: one present in the blood and the other in blood vessel walls. In mammals, fibronectin is important for the development of blood vessels before birth, but whether it is continuously required for blood vessel homeostasis from birth to adulthood is unknown. We present important results from three genetically modified mouse models, which show that at least one form of fibronectin is required for the proper function and integrity of blood vessels during this period.

Classified as: department anatomy cell biology
Published on: 8 Aug 2018

To all members of the Faculty of Medicine,

Following weeks of remediation efforts we continue to make steady progress on the road to returning the McIntyre Building to normal operations. Roughly half of the building has re-opened, with occupants of the 7th floor and up returning to the building. A great deal of work remains however, in particular with respect to the lower floors. While the goal is to be able to re-open the 1st to 6th floors as quickly as possible, portions of these lower floors are expected to remain closed for several months.

Published on: 2 Aug 2018

To all members of the Faculty of Medicine,

As previously communicated, as of last Friday McIntyre Floors 7 and higher were reopened for all faculty and staff members and students, accessible via the 6th floor Pine entrance. With three of the four ventilation systems servicing this area of the building returning to operation, temperatures on these floors continued to drop over the weekend and are now within their normal range, with the exception of small pockets of warmer areas that are serviced by the one HVAC system that remains to be cleaned.

Published on: 30 Jul 2018

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