McGill.CA / Department of Chemistry / Research / Instruments and facilities

Mass Spectroscopy (MS) Facility

The McGill Chemistry Department Mass Spectrometry Facility (MSF) offers a comprehensive range of mass spectrometry techniques to researchers, using six mass spectrometers equipped with a range of ionization methods. The facility’s primary role is to support chemical research conducted within the Department; but can also serve other McGill departments, as well as outside academic and industrial groups.
Some of the instruments can be operated by our department users themselves following user training e.g. LCQ, Scion and Polaris Q.
The MSF is located in room 21 in the basement of the Department. Everyone is encouraged to use the services offered at the Facility and to get in touch with its personnel to discuss your questions in details.
A sample submission request form has to be filled when a sample is submitted for analysis.File sample_submission_request_form.docx

List of available MS

A. LCQ-API (Atmospheric pressure ionization) Ion Trap (THERMO)

Capability:

  • ESI +ions (M+H / M+cation) ;--ions (M-H, M+anion); multiple charging .APCI +ions (M+H); --ions (M-H) ; some fragmentation
  • LC/MS

B. Exactive Plus Orbitrap-API/ (High Resolution/Accurate Mass) (THERMO)

Capability:

  • ESI +ions (M+H / M+cation) ;--ions (M-H, M+anion); multiple charging
  • APCI +ions (M+H); --ions (M-H) ; some fragmentation
  • HR (high resolution); Accurate mass (elemental composition)
  • LC/MS 
  • Autosampler

C. MALDI  Autoflex III- TOF-(BRUKER)

Capability:

  • Particularly high molecular weight compounds e.g. peptides, proteins, polymers
  • Positive and Negative ions
  • Possibility of proteins sequencing

D. GC/MS Polaris Q-Ion Trap (THERMO)

Capability:

  • EI/CI Direct Probe  positive and negative ions
  • EI/CI GC/MS
  • MS(n)
  • Autosampler

E. GC/MS Scion-Single quadrupole (Bruker)

Capability

  • EI/CI Direct Probe  positive and negative ions
  • EI/CI GC/MS
  • Autosampler

F.  Maxis API (Atmospheric pressure ionization) QqTOF (Bruker)

Capability:

  • ESI +ions (M+H / M+cation) ;--ionss (M-H, M+anion); multiple charging
  • APCI +ions (M+H); --ions (M-H); some fragmentation
  • APPI + and - ions
  • Direct Probe
  • HR (high resolution); Accurate mass (elemental composition)
  • MS(2)
  • LC/MS 
  • Autosampler
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