Dr. Jeremy Van Raamsdonk

My research focuses on the genetics and biology of aging and the pathogenesis of neurodegenerative disease. I am also highly interested in biological resilience and how that contributes to longevity and neurodegeneration. Much of my work focusses on the mitochondria as it highly involved in lifespan, resilience and neurodegenerative disease. To complete these studies, I primarily use a simple genetic model organism, the worm C. elegans. My work in Geroscience aims to advance our understanding of the molecular mechanisms underlying longevity and biological resilience and apply that knowledge to promote healthy aging and develop novel treatments for neurodegenerative disease. I use a translational approach in which we perform initial experiments in C. elegans in order to prioritize subsequent experiments in mammalian models.