Dr. Marta Kaminska
Associate Professor - Department of Medicine, Division of Experimental Medicine
Respiratory issues in neurological diseases, particularly sleep-related breathing disorders such as obstructive sleep apnea (OSA). It is divided in two themes:
In theme 1, she studies the interaction between OSA and central nervous system disorders, such as multiple sclerosis and Parkinson's disease. On the one hand, neurological disorders may lead to OSA. On the other, treating OSA may help specific symptoms and quality of life in those patients.
Theme 2 relates to various aspects of respiratory care of patients with neuromuscular diseases (which cause muscle weakness). Amyotrophic lateral sclerosis (ALS) is such a disease, causing progressive weakening of respiratory muscles leading to respiratory failure. She has been studying the measurement of respiratory strength, lung volume recruitment manoeuvres (a technique that helps maintain lung health), and new modes of adjusting a ventilator for long term use at home.
1. Cognitive function in patients with Parkinson's disease and obstructive sleep apnea: effect of CPAP treatment.
2. Home ventilation in ALS: randomized trial of ST vs iVAPS modes.
3. Retrospective study of home noninvasive ventilation in COPD and obesity hypoventilation syndrome through the Quebec National Program o Home Ventilatory Assistance Impact on hospitalizations.