Dr. Thomas Ming Swi Chang
Professor Emeritus - Department of Physiology, Department of Medicine, Division of Experimental Medicine and Department of Biomedical Engineering
Artificial cells in biotechnology and medicine with emphasis on potential applications in medicine
Different types of artificial cells are being investigated for many medical conditions. Contents of artificial cells include enzymes, hemoglobin, cells, genetically engineered cells and other biotechnological materials. The size ranges from cellular dimensions to the higher millimetre ranges (for cell culture and genetically engineered cells) and down to the nanometer range (for blood substitutes and delivery of protein and macromolecules) and even to the macromolecular range (e.g. cross-linked hemoglobin-enzymes as blood substitutes). More details can be obtained from our website: www.artcell.mcgill.ca
(1) REVIEW ON ARTIFICIAL CELLS: 2019 free open access
(2) REVIEW ON HEMOPERFUSION 2017
(3) PAPERS ON NOVEL NANOBIOTHERAPEUTIC WITH ENHANCED RBC FUNCTIONS
2017 summary
2015 90 mins Hemorrhagic shock
2018 Long term safety and immunology or www.artcell.mcgill.ca/safety.immune.pdf
2016 Temperature stability 4C to 70C
(4) 2021 Nanobiotheraapeutic for melanoma: J Artificial Cell Nanmedicine Biotehch