Liam Carroll

Name: Liam Carroll

Level at MPU: MSc.

Email: liam.carroll [at]

Supervisor(s): Dr. Shirin Enger

Research interests: Dynamic PET, Device Development, nuclear medicine


Research summary

Positron Emission Tomography (PET) is a nuclear medicine
imaging technique that tracks the location of radio-labelled molecules through the
human body. This technique has a wide range of applications from disease
detection to pharmacokinetic analysis of new drugs. PET data can be viewed
statically (s single integrated image) or dynamically (following the
time-activity curve of the tissue of interested). Dynamic scans are more
interesting due to the additional kinetic information they provide but require
an additional input in the form of the time activity curve in the patient's
arteries called the arterial input function (AIF). The AIF is traditionally
acquired using invasive arterial blood sampling, an invasive and expensive procedure,
which limits dynamic PET to academic PET centers. This project aims to develop
and optimize a non-invasive positron detector to measure the arterial input function
(AIF) in dynamic positron emission tomography (PET) imaging. This would allow
dynamic PET scans to be acquired in any clinic where static PET is normally
performed. We are using fast plastic scintillators coupled to optical fiber and
SiPMTs to detect positrons leaving the radial/ulnar arteries. This project is
currently in a prototype phase.


CSACS summer student program (2014)