Interdepartmental Honours Program in Immunology (IHI)

Application | U1 Complementary Courses | U2 Complementary Courses | U3 Complementary Courses

The IHI program is a 75-credit program involving the Departments of Biochemistry, Microbiology and Immunology, and Physiology, and it incorporates elements from each of these disciplines. Since immunology is a key area of biomedical research and is critical to our understanding of the patho-physiology of many immune-mediated diseases, the program provides an excellent foundation for students interested in pursuing a career in biomedical research and/or medicine.

The program consists of 48 Required credits in basic science courses, including cell and molecular biology, microbiology and immunology, biochemistry and physiology. There are also 27 Complementary credits which allow for specialization in immunology and related disciplines. To graduate from IHI, students must have a minimum CGPA of 3.30 and must pass five immunology courses (MIMM 214, MIMM 314, MIMM 414 , PHGY 419D1D2, PHGY 513, and one of BIOC 503, MIMM 509, PHGY 531) with a minimum grade of B

The coordinators of the program are heather.melichar [at] mcgill.ca (Dr. Heather Melichar), judith.mandl [at] mcgill.ca (Dr. Judith Mandl )andanastasiya.nyzhnyk [at] mcgill.ca ( Dr. Ana Nijnik)

ihi_prospective_student_info_session_-_apr_10_2024.pdf

The IHI Research Project

One of the core components and most rewarding and challenging aspects of the IHI is the Immunology Research Project (PHGY 419D1D2) course. Each student conducts their own independent research project under the supervision of a professor of immunology and participates in all aspects of the project on a collaborative basis with the supervisor and other members of the supervisor’s laboratory. Students gain a first-hand understanding and appreciation of biomedical research by contributing to the design of meaningful experiments, by collecting, analyzing and interpreting the experimental data, and by giving oral presentations and submitting written reports of their work.

A list of approved supervisors can be found here potential_research_supervisors.pdf

If you are considering a supervisor not on the list you must contact your course coordinator for approval.

Student Eligibility

To be admitted to the IHI program, a student must have a) completed the 6 U1 IHI Required Courses, b) obtained a grade of B or higher in MIMM 214, c) taken at least 27 U1 credits, and d) achieved a CGPA of 3.30 or higher. Students may enter the program from Biochemistry, Microbiology and Immunology, Physiology, and other biomedical departments such as Anatomy and Cell Biology or Pharmacology and Therapeutics. Since enrolment is limited, admission may be denied if demand exceeds the number of available places. If places are available students may also be admitted up to the end of their U2 year.

Application Process

Prospective applicants to the IHI program must carefully review all eligibility and program requirements before beginning the application process. To apply, students must complete the following steps:

1. Fill out the IHI online application form.
2. Upload a CV as a single PDF file (maximum 3 pages) to the application form.

Upon submitting the application, applicants will receive an acknowledgment email confirming receipt of their submission.

For inquiries or assistance, please email undergrad2.physiology [at] mcgill.ca (subject: IHI%20Program) or undergrad.microimm [at] mcgill.ca (subject: IHI%20Program) .

Applications are scheduled to open during the Winter 2025 term.

Required Courses (48 credits)

U1 Required Courses (20 credits)

Course #	Title	Credits
BIOL 200 Molecular Biology 3 Credits Offered in the: Fall Winter Summer Biology (Sci): The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression. Offered by: Biology Fall 3 hours lecture, 1 hour optional tutorial Prerequisite: BIOL 112 or equivalent Corequisite: CHEM 212 or equivalent, or CHEM 204 Terms Fall 2024 Instructors Kenneth E M Hastings, Paul Lasko, Shaun Turney, Rodrigo Reyes Lamothe, Serge Champetier	Molecular Biology
BIOL 201 Cell Biology & Metabolism 3 Credits Offered in the: Fall Winter Summer Biology (Sci): This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle. Offered by: Biology Winter 3 hours lecture, 1 hour optional tutorial Prerequisite: BIOL 200. Restriction: Not open to students who have taken or are taking ANAT 212 or BIOC 212 Terms Winter 2025 Instructors Gary J Brouhard, Siegfried Hekimi, Huanquan Zheng, Serge Champetier or BIOC 212 Molec Mechanisms of Cell Funct 3 Credits Offered in the: Fall Winter Summer Biochemistry: An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division. Offered by: Biochemistry Winter Prerequisite: BIOL 200 Restrictions: A non-terminal course intended to be followed by BIOC 311; BIOC 312 in the U2 year. Not open to students who have taken or are taking BIOL 201 or ANAT 212. Terms Winter 2025 Instructors Maria Vera Ugalde, Arnim Pause, Dieter Reinhardt, Lawrence Kazak, Katie Cockburn	Cell Biology and Metabolism Molecular Mechanisms of Cell Function	3 3
CHEM 212 Intro Organic Chemistry 1 4 Credits Offered in the: Fall Winter Summer Chemistry: A fundamental study of aliphatic compounds and saturated functional groups including modern concepts of bonding, reaction mechanisms, conformational analysis, spectroscopy, and stereochemistry. Offered by: Chemistry Fall, Summer Prerequisite: CHEM 110 and CHEM 120 or equivalent. Restriction: Not open to students registered in Chemistry or Biochemistry. Not open to students who have taken or are taking CHEM 211, CHEM 242, or equivalent. Each lab section is limited enrolment Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page (http://www.chemistry.mcgill.ca/advising/outside/equivalent.htm). Terms Fall 2024 Instructors Danielle K Vlaho, Mitchell J Huot, Pallavi Sirjoosingh, Youla S Tsantrizos, Laura Pavelka, Nathan Luedtke	Organic Chemistry 1	4
CHEM 222 Intro Organic Chemistry 2 4 Credits Offered in the: Fall Winter Summer Chemistry: Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics. Offered by: Chemistry Winter, Summer Prerequisite: CHEM 212 or CHEM 242 or equivalent. Restriction: Not open to Chemistry or Biochemistry students. Not open to students who have taken or are taking CHEM 234 or CHEM252. Terms Winter 2025 Instructors Danielle K Vlaho, Mitchell J Huot, Pallavi Sirjoosingh, Nicolas Moitessier, Nathan Luedtke	Organic Chemistry 2	4
MIMM 211 Introductory Microbiology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): A general treatment of microbiology bearing specifically on the biological properties of microorganisms. Emphasis will be on procaryotic cells. Basic principles of microbial genetics are also introduced. Offered by: Microbiology & Immunology Fall 3 hours of lecture Corequisite: BIOL 200 Terms Fall 2024 Instructors Benoit Cousineau, Dao Nguyen, Greg J Matlashewski, Samantha Gruenheid, Jasmin K Chahal, Corinne Maurice, Francois A Le Mauff or PHGY 209 Mammalian Physiology 1 3 Credits Offered in the: Fall Winter Summer Physiology: Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems. Offered by: Physiology Fall 3 hours lectures weekly Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent. Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200. Restriction: For students in the Faculty of Science, and other students by permission of the instructor Terms Fall 2024 Instructors Melissa A Vollrath, David S Ragsdale, Alvin Shrier, Erik P Cook, Céline Aguer	Introductory Microbiology Mammalian Physiology 1	3 3
MIMM 214 Intro Immun: Elem of Immunity 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): Basic immunology, organs and cells, elements of innate immunity, phagocytes, complement, elements of adaptive immunity, B-cells, T-cells, antigen presenting cells, MHC genes and molecules, antigen processing and presentation, cytokines and chemokines. Emphasis on anatomy and the molecular and cellular players working together as a physiological system to maintain human health. Offered by: Microbiology & Immunology Prerequisite: BIOL 200 Corequisite: BIOL 201 or ANAT 212/BIOC 212 Terms Winter 2025 Instructors Jasmin K Chahal	Introduction to Immunology	3

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U2 Required Courses (13 credits)

ANAT 261 Intro to Dynamic Histology 4 Credits Offered in the: Fall Winter Summer Anatomy & Cell Biology: An introduction to light and electron microscopic anatomy in which cell and tissue dynamics will be explored in the principal tissues and organs of the body. Offered by: Anatomy and Cell Biology Fall 3 hours lectures, 2 hours laboratory Must be taken in U1 by students in Anatomy and Cell Biology programs Prerequisite: BIOL 112 or CEGEP equivalent Restriction: Open to students in biological sciences and others by special permission Terms Fall 2024 Instructors Craig A. Mandato, Carlos R Morales	Introduction to Dynamic Histology	4
BIOC 311 Metabolic Biochemistry 3 Credits Offered in the: Fall Winter Summer Biochemistry: The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction. Offered by: Biochemistry Fall Prerequisites: BIOL 200, BIOL 201 or BIOC 212, CHEM 222 or CHEM 234 Terms Fall 2024 Instructors Maxime Denis, Vincent Giguere, Kalle Gehring, Lawrence Kazak	Metabolic Biochemistry	3
BIOC 312 Biochemistry of Macromolecules 3 Credits Offered in the: Fall Winter Summer Biochemistry: Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis). Offered by: Biochemistry Winter Prerequisites: BIOC 311, BIOL 200, BIOL 201 or BIOC 212 Terms Winter 2025 Instructors Sidong Huang, Stephane Richard, Nahum Sonenberg, Michel Tremblay, Josee Dostie, Vincent Giguere, Maria Vera Ugalde	Biochemistry of Macromolecules	3
MIMM 314 Intermediate Immunology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): An intermediate-level immunology course covering the cellular and molecular basis of lymphocyte development and activation in immune responses in health and disease. Offered by: Microbiology & Immunology Winter 3 hours of lecture Prerequisite: MIMM 214 Terms Winter 2025 Instructors Ciriaco Piccirillo, Irah King, Heather Melichar	Immunology	3

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U3 Required Courses (15 credits)

PHGY 531 Topics in Applied Immunology 3 Credits Offered in the: Fall Winter Summer Physiology: Seminar format course in which experts in immunologic mechanisms of resistance against a variety of infectious diseases, including AIDS, malaria, and tuberculosis oversee student moderators in their presentation of recent scientific literature in the field. Offered by: Physiology Winter Restriction: Permission of the instructor. U3 InterDept. Honours Immunology students and graduate students with strong immunology background i.e. PHGY 513 and BIOC 503 Terms Fall 2024 Instructors Judith N Mandl, Paul Clarke, Irah King, Heather Melichar, Pouya Bashivan	Topics in Applied Immunology	3
PHGY 419D1 Immunology Research Project 4.5 Credits Offered in the: Fall Winter Summer Physiology: Individual research projects in immunology under the guidance of staff members in the three participating departments: Physiology, Biochemistry, and Microbiology and Immunology. Offered by: Physiology Fall 15 hours lab/week Restriction: Enrolment restricted to U3 Interdepartmental Honours Immunology students or permission of instructors Students must register for both PHGY 419D1 and PHGY 419D2. No credit will be given for this course unless both PHGY 419D1 and PHGY 419D2 are successfully completed in consecutive terms Terms Fall 2024 Instructors Judith N Mandl, Anastasia Nijnik, Heather Melichar	Immunology Research Project	4.5
PHGY 419D2 Immunology Research Project 4.5 Credits Offered in the: Fall Winter Summer Physiology: See PHGY 419D1 for course description. Offered by: Physiology Winter 15 hours lab/week Prerequisite: PHGY 419D1 No credit will be given for this course unless both PHGY 419D1 and PHGY 419D2 are successfully completed in consecutive terms Restriction: Enrolment restricted to U3 Interdepartmental Honours Immunology students or permission of instructors Terms Winter 2025 Instructors Anastasia Nijnik, Monroe W Cohen, Judith N Mandl	Immunology Research Project	4.5
PHGY 513 Translational Immunology 3 Credits Offered in the: Fall Winter Summer Physiology: Advanced key concepts in immunology as they relate to health and disease, including infectious diseases, non-infectious diseases and autoimmunity, and cancer immunology. Offered by: Physiology Winter 3 hours lectures Prerequisite: MIMM 314 or PHGY 313 or permission of the instructor Terms Winter 2025 Instructors Daniela Quail, Marcel A Behr, Joyce Rauch, Jack P Antel, Nicole F Bernard, Erwin Schurr, Brian Ward, Jörg H Fritz, Anastasia Nijnik, Judith N Mandl	Cellular Immunology	3

Complementary Courses (27 credits)

U1 Complementary Courses (6 credits)

3 credits selected from:

BIOL 373 Biometry 3 Credits Offered in the: Fall Winter Summer Biology (Sci): Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages. Offered by: Biology Fall 2 hours lecture and 2 hours laboratory Prerequisite: MATH 112 or equivalent You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Terms This course is not scheduled for the 2024 academic year Instructors There are no professors associated with this course for the 2024 academic year	Biometry	3
MATH 203 Principles of Statistics 1 3 Credits Offered in the: Fall Winter Summer Mathematics & Statistics (Sci): Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions). Offered by: Mathematics and Statistics No calculus prerequisites Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps. You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult http://www.mcgill.ca/students/transfercredit for information regarding transfer credits for this course. Terms Fall 2024 Winter 2025 Instructors Jose Andres Correa, David A Stephens Alia Sajjad	Principles of Statistics 1	3
PSYC 204 Intro to Psychological Stats 3 Credits Offered in the: Fall Winter Summer Psychology: The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance. Offered by: Psychology Fall and Winter Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300 This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336 You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Terms Fall 2024 Winter 2025 Instructors Jens Kreitewolf Jens Kreitewolf	Introduction to Psychological Statistics	3

plus 3 credits selected from:

ANAT 214 Systemic Human Anatomy 3 Credits Offered in the: Fall Winter Summer Anatomy & Cell Biology: Introduction to the gross anatomy of the various organ systems of head, neck and trunk regions of the human body. Emphasis on functional anatomy. Laboratory component includes exploration of the human body through cadaveric prosections, imaging and other materials. Offered by: Anatomy and Cell Biology Fall 2 hours lectures, 2 hours laboratory Prerequisites: BIOL 112 (or CEGEP equivalent), PHGY 209 and PHGY 210 This course is limited in size, with guaranteed admission for all students enrolled in the Department of Anatomy and Cell Biology. Students in other programs will be permitted to enroll as space allows. Terms Fall 2024 Instructors Campbell Rolian, Gabriel Venne	Systematic Human Anatomy	3
ANAT 262 Intro Molecular &Cell Biol 3 Credits Offered in the: Fall Winter Summer Anatomy & Cell Biology: The architectural, functional and temporal continuity of organelles and the cytoskeleton of mammalian cells is introduced as well as their functional integration in the phenomena of exocytosis, endocytosis, protein trafficking and cell motility and adhesion. Offered by: Anatomy and Cell Biology Winter 3 hours lecture Corequisites: ANAT 212 or BIOC 212 or BIOL 201 Restriction: Open to students in biological sciences and others by special permission Terms Winter 2025 Instructors John Presley, Ursula Stochaj, Susanne Bechstedt, Khanh Huy Bui	Introductory Molecular and Cell Biology	3
BIOL 202 Basic Genetics 3 Credits Offered in the: Fall Winter Summer Biology (Sci): Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences. Offered by: Biology Winter 3 hours lecture, 1 hour optional tutorial per week Prerequisite: BIOL 200 or BIOL 219 Restriction: Not open to students who have taken or are taking LSCI 204 or BIOL 302. Terms Winter 2025 Instructors Nam Sung Moon, Laura Nilson, Daniel J Schoen, David Hipfner, Serge Champetier	Basic Genetics	3
BIOL 205 Functional Biol of Plnts&Anmls 3 Credits Offered in the: Fall Winter Summer Biology (Sci): Unified view of form and function in animals and plants. Focus on how the laws of chemistry and physics illuminate biological processes relating to the acquisition of energy and materials and their use in movement, growth, development, reproduction and responses to environmental stress. Offered by: Biology Winter 3 hours lecture, optional conference hour Prerequisites: BIOL 200 and PHYS 101 or 131 or equivalent Corequisite: ANAT 212/BIOC 212 or BIOL 201 Terms Winter 2025 Instructors Jon Sakata, Rowan Barrett, Fiona M Soper	Biology of Organisms	3
BIOL 304 Evolution 3 Credits Offered in the: Fall Winter Summer Biology (Sci): A comprehensive introduction to evolutionary biology. It covers both short-term and long-term evolutionary processes. Topics include the history of life, the origin of species, adaptation, natural selection and sexual selection. Offered by: Biology Fall 2 hours lecture 3 hours lab Prerequisite: BIOL 205 and BIOL 215 or ENVR 202 Terms Fall 2024 Instructors Andrew Hendry, Hans Carl E Larsson	Evolution	3
CHEM 203 Survey of Physical Chemistry 3 Credits Offered in the: Fall Winter Summer Chemistry: The fundamentals of thermodynamics and chemical kinetics with applications to biomolecular systems. Thermodynamic and kinetic control of biological processes. Offered by: Chemistry Fall Prerequisites: CHEM 110 and CHEM 120 or equivalent. Restrictions: Intended for students in biological science programs requiring only one course in physical chemistry. Not open to students who have taken or are taking CHEM 204 or CHEM 213 or CHEM 223 and CHEM 243. Terms Fall 2024 Instructors Pallavi Sirjoosingh or CHEM 204 Physical Chem/Biological Scis1 3 Credits Offered in the: Fall Winter Summer Chemistry: Similar to CHEM 223/CHEM 243. Emphasis on the use of biological examples to illustrate the principles of physical chemistry. The relevance of physical chemistry to biology is stressed. Offered by: Chemistry Fall, Winter Prerequisites: CHEM 110 and CHEM 120 or equivalent and one full course in calculus Restriction: Not open to students who have taken or are taking CHEM 203 or CHEM 213. Terms Fall 2024 Winter 2025 Instructors Rustam Khaliullin Lucas Caire da Silva	Survey of Physical Chemistry Physical Chemistry/Biological Sciences 1	3 3
CHEM 287 Intro Analytical Chemistry 2 Credits Offered in the: Fall Winter Summer Chemistry: Qualitative and quantitative analysis. A survey of methods of analysis including theory and practice of semimicro qualitative analysis and representative gravimetric, volumetric and instrumental methods. Offered by: Chemistry Fall Prerequisites: CHEM 110 and CHEM 120, or CHEM 115, or equivalent. Corequisite: Students in CHEM 287 are required to take the laboratory, CHEM 297, either simultaneously with CHEM 287 or in the term following CHEM 287. Restrictions: Not open to students who have taken CHEM 257D1/D2 or CHEM 277D1/D2. Terms This course is not scheduled for the 2024 academic year Instructors There are no professors associated with this course for the 2024 academic year and CHEM 297 Intro Analytical Chem. Lab. 1 Credits Offered in the: Fall Winter Summer Chemistry: Introductory experiments in analytical chemistry emphasizing classical and instrumental methods of quantitative analysis. Offered by: Chemistry Fall, Winter Prerequisites: CHEM 110 and CHEM 120, or CHEM 115, or equivalent. Pre- or Co-requisite: CHEM 287. Restriction: Not open to students who have taken CHEM 257D1/D2 or CHEM 277D1/D2. Terms This course is not scheduled for the 2024 academic year Instructors There are no professors associated with this course for the 2024 academic year	Introductory Analytical Chemistry Introductory Analytical Chemistry Laboratory	2 2
COMP 202 Foundations of Programming 3 Credits Offered in the: Fall Winter Summer Computer Science (Sci): Introduction to computer programming in a high level language: variables, expressions, primitive types, methods, conditionals, loops. Introduction to algorithms, data structures (arrays, strings), modular software design, libraries, file input/output, debugging, exception handling. Selected topics. Offered by: Computer Science 3 hours Restrictions: Not open to students who have taken or are taking COMP 204, COMP 208, or GEOG 333; not open to students who have taken or are taking COMP 206 or COMP 250. COMP 202 is intended as a general introductory course, while COMP 204 is intended for students in life sciences, and COMP 208 is intended for students in physical sciences and engineering. To take COMP 202, students should have a solid understanding of pre-calculus fundamentals such as polynomial, trigonometric, exponential, and logarithmic functions. Terms Fall 2024 Winter 2025 Instructors Faten M'hiri Faten M'hiri	Foundations of Programming	3
COMP 250 Intro to Computer Science 3 Credits Offered in the: Fall Winter Summer Computer Science (Sci): Mathematical tools (binary numbers, induction,recurrence relations, asymptotic complexity,establishing correctness of programs). Datastructures (arrays, stacks, queues, linked lists,trees, binary trees, binary search trees, heaps,hash tables). Recursive and non-recursivealgorithms (searching and sorting, tree andgraph traversal). Abstract data types. Objectoriented programming in Java (classes andobjects, interfaces, inheritance). Selected topics. Offered by: Computer Science 3 hours Prerequisite(s): MATH 140 or equivalent. COMP 202 or COMP 204 or COMP 208 (or equivalent). Corequisite(s): MATH 133 Restriction(s): Not open to students who have taken or are taking ECSE 250. Terms Fall 2024 Winter 2025 Instructors Giulia Alberini Giulia Alberini	Introduction to Computer Science	3
MATH 204 Principles of Statistics 2 3 Credits Offered in the: Fall Winter Summer Mathematics & Statistics (Sci): The concept of degrees of freedom and the analysis of variability. Planning of experiments. Experimental designs. Polynomial and multiple regressions. Statistical computer packages (no previous computing experience is needed). General statistical procedures requiring few assumptions about the probability model. Offered by: Mathematics and Statistics Winter Prerequisite: MATH 203 or equivalent. No calculus prerequisites Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps. You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Terms Winter 2025 Instructors Tharshanna Nadarajah	Principles of Statistics 2	3
MIMM 211 Introductory Microbiology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): A general treatment of microbiology bearing specifically on the biological properties of microorganisms. Emphasis will be on procaryotic cells. Basic principles of microbial genetics are also introduced. Offered by: Microbiology & Immunology Fall 3 hours of lecture Corequisite: BIOL 200 Terms Fall 2024 Instructors Benoit Cousineau, Dao Nguyen, Greg J Matlashewski, Samantha Gruenheid, Jasmin K Chahal, Corinne Maurice, Francois A Le Mauff	Introductory Microbiology	3
MIMM 212 Laboratory in Microbiology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): This laboratory course is designed to complement MIMM 211. Sessions introduce general techniques peculiar to the handling of microorganisms. Offered by: Microbiology & Immunology Fall 3 hours laboratory, 1 hour lecture, 1 hour follow-up Corequisite: MIMM 211 Terms Fall 2024 Instructors Jasmin K Chahal	Laboratory in Microbiology	3
PHGY 209 Mammalian Physiology 1 3 Credits Offered in the: Fall Winter Summer Physiology: Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems. Offered by: Physiology Fall 3 hours lectures weekly Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent. Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200. Restriction: For students in the Faculty of Science, and other students by permission of the instructor Terms Fall 2024 Instructors Melissa A Vollrath, David S Ragsdale, Alvin Shrier, Erik P Cook, Céline Aguer	Mammalian Physiology 1	3
PHGY 210 Mammalian Physiology 2 3 Credits Offered in the: Fall Winter Summer Physiology: Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems. Offered by: Physiology Winter 3 hours lectures weekly Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisite: BIOL 200, BIOL 201, BIOC 212, CHEM 212 or equivalent. Restriction: For students in the Faculty of Science, and other students by permission of the instructor Although PHGY 210 may be taken without the prior passing of PHGY 209, students should note that they may have some initial difficulties because of lack of familiarity with some basic concepts introduced in PHGY 209 Terms Winter 2025 Instructors Melissa A Vollrath, Tomoko Takano, Anne-Marie Lauzon, John H White, Céline Aguer	Mammalian Physiology 2	3

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U2 Complementary Courses (12 credits)

6 credits selected from

BIOC 220 Lab Meth in Biochem&Mol Biol 1 3 Credits
Offered in the:

Fall

Winter

Summer

Biochemistry: Introduction to key methodologies for the isolation, detection and characterization of proteins, lipids, nucleic acids and subcellular fractions, including spectrophotometry, assays of enzymatic activities and chromatographic and electrophoretic methods. Analysis of biochemical data.

Offered by: Biochemistry

Prerequisite(s): BIOL 200

Corequisite(s): BIOC 212 and CHEM222

Restriction(s): Not open to students who have taken or are taking BIOL 301. Open to students in Biochemistry programs, others with permission of the instructor.

Terms

Winter 2025

Instructors

Natasha Chang

and

BIOC 320 Lab Meth in Biochem&Mol Biol 2 3 Credits
Offered in the:

Fall

Winter

Summer

Biochemistry: Modern molecular-biological methods for isolation and characterization of nucleic acids and for analysis of RNA and protein expression, including: plasmid expression, isolation, restriction and ligation; electrophoretic methods and Western blotting; PCR and qPCR applications; immunofluorescence microscopy and basic bioinformatics approaches.

Offered by: Biochemistry

Prerequisite(s): BIOC 220

Restriction(s): Not open to students who have taken or are taking BIOL 301. Open to students in Biochemistry programs; others with permission of the instructor.

Terms

Fall 2024

Instructors

Jose Guerreiro Teodoro

MIMM 384 Molecular Microbiology Lab 3 Credits
Offered in the:

Fall

Winter

Summer

Microbiology and Immun (Sci): A series of laboratory exercises in molecular biology and microbial genetics during the Fall term. As part of a term paper writing project, students will explore contemporary research subjects that represent the wide interests of the Microbiology and Immunology departmentâ•Žs faculty. The general objective is to provide practical and theoretical introduction to the technology and methodology used in contemporary microbiology research.

Offered by: Microbiology & Immunology

Prerequisite(s): MIMM 211 and MIMM 212

Corequisite(s): MIMM 323 and MIMM 324

Restriction(s): Not open to students who are taking or have taken MIMM 386D1/D2.

Terms

Fall 2024

Instructors

Benoit Cousineau, Jasmin K Chahal

MIMM 385 Laboratory in Immunology 3 Credits
Offered in the:

Fall

Winter

Summer

Microbiology and Immun (Sci): This laboratory course allows students to gain expertise in following protocols and performing key techniques in immunology. Students also develop basic experimental design and scientific thinking skills by designing their own experiments based on available reagents to solve a problem. Students learn to keep a lab book and communicate scientific findings in written and oral form.

Offered by: Microbiology & Immunology

Prerequisite(s): MIMM 211, MIMM 212, MIMM 214 (MIMM 384 highly recommended).

Corequisite(s): MIMM 314

Not open to students who are taking or have taken MIMM 386D1/D2.

Terms

Winter 2025

Instructors

Samantha Gruenheid

PHGY 212 Introductory Physiology Lab 1 1 Credits
Offered in the:

Fall

Winter

Summer

Physiology: Exercises illustrating fundamental principles in physiology: Biological Signals Acquisitions, Blood, Immunology, Neurophysiology, Neuromuscular Physiology.

Offered by: Physiology

(One 3-hour lab and one 1-hour lecture every second week.)

Corequisite: PHGY 209.

Restrictions: Required for Physiology students enrolled in PHGY 209. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.

Note: For students in a Physiology program, PHGY 212 should be taken concurrently with PHGY 209.

Terms

Fall 2024

Instructors

Melissa A Vollrath, Mladen I Glavinovic, Judith N Mandl

and

PHGY 213 Introductory Physiology Lab 2 1 Credits
Offered in the:

Fall

Winter

Summer

Physiology: Exercises illustrating fundamental principles in physiology: Central Nervous System, Cardiovascular, Respiration, Exercise Physiology, Molecular Endocrinology.

Offered by: Physiology

(One 3-hour lab and one 1-hour lecture every second week.)

Prerequisite: PHGY 212

Corequisite: PHGY 210.

Restrictions: Required for Physiology students enrolled in PHGY 210. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.

Note: For students in a Physiology program, PHGY 213 should be taken concurrently with PHGY 210.

Terms

Winter 2025

Instructors

Michael R Guevara, Sheldon A Magder, John H White, Melissa A Vollrath

and

BIOL 301 Cell and Molecular Laboratory 4 Credits
Offered in the:

Fall

Winter

Summer

Biology (Sci): An introduction to biology research and communication with a focus on cell and molecular biology. Through conducting a series of project-based experiments and writing a final report, molecular and synthetic biology techniques such as gene cloning, manipulation, protein isolation and characterization and how research is conducted, analyzed and communicated will be addressed. In addition, an introduction to bioinformatics methods and their role in analysis will be provided.

Offered by: Biology

Fall or Winter

1 hour lecture and one 6-hour laboratory

Prerequisites: BIOL 200, BIOL 201 (or ANAT 212/BIOC 212); or BIOL 219

Restrictions: Not open to students who have taken or are taking BIOC 300, or BIOC 220 and BIOC 320. Requires departmental approval.

For approval email maxime.leroux [at] mcgill.ca. Specify your ID number as well as the term and two lab day preferences.

Terms

Fall 2024

Winter 2025

Instructors

Arnold L Hayer, Maxime Leroux, Paul M Harrison, Huanquan Zheng

Huanquan Zheng, Maxime Leroux, Paul M Harrison, Arnold L Hayer

Laboratory Methods in Biochemistry and Molecular Biology 1

Laboratory Methods in Biochemistry and Molecular Biology 2

Molecular Microbiology Lab

Laboratory in Immunology

Introductory Physiology Laboratory 1

Introductory Physiology Laboratory 2

Cell and Molecular Laboratory

plus 6 credits selected from:

ANAT 365 Cellular Trafficking 3 Credits Offered in the: Fall Winter Summer Anatomy & Cell Biology: This course explores the fundamental mechanisms that govern the organizations of intracellular membranes, how vesicle generation is signaled, how the membranes curve and bud, and how vesicles know where to go and fuse. In addition to intracellular vesicles, the principles of mitochondrial dynamics and process of cellular autophagy are examined. Also, there is a focus on "Applied Cell Biology", with respect to how the exquisite regulation of cellular transport plays a central role in complex biological systems. A series of modules will take students through the mechanisms of cellular polarity, neurotransmission, metabolic cell biology, pathogen invasion, and more. The emphasis is on the morphological aspects of the processes, and on the major techniques that led to discovery. Offered by: Anatomy and Cell Biology Fall 3 hours lectures Prerequisites: ANAT 261, ANAT 262, PHGY 209, or by permission of instructor Terms Fall 2024 Instructors Natalie Zeytuni, Heidi M McBride, Timothy E Kennedy, Thomas Stroh, John Presley, Wayne Steven Sossin, Jennifer L Estall	Cellular Trafficking	3
BIOL 300 Molecular Biology of the Gene 3 Credits Offered in the: Fall Winter Summer Biology (Sci): A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction. Offered by: Biology Fall 3 hours lecture Prerequisites: BIOL 219 or BIOL 200 plus either BIOL 201 or ANAT 212/BIOC 212 Terms Fall 2024 Instructors Frieder B Schöck, Nam Sung Moon	Molecular Biology of the Gene	3
BIOL 314 Molecular Biology of Cancer 3 Credits Offered in the: Fall Winter Summer Biology (Sci): The molecular basis of human cancers, including analyzing the events that promote the formation of oncogenes and inhibit tumour suppressor genes, the biochemical properties of the proteins encoded by these genes, and their functions. Current molecular targets for cancer therapy and the concepts and consequences of inheriting mutations in genes that predispose to cancer. Offered by: Biology Fall 3 hours lecture Prerequisites: BIOL 200, and BIOL 201 or ANAT 212 /BIOC 212; or BIOL 219. Terms Winter 2025 Instructors David Dankort	Molecular Biology of Oncogenes	3
CHEM 302 Intrdctry Organic Chemistry 3 3 Credits Offered in the: Fall Winter Summer Chemistry: Topics covered may include the following: Aromatic compounds, heterocyclic chemistry, sulfur and phosphorus chemistry, organosulfur and organophosphorus compounds, and biomolecules such as lipids, carbohydrates, amino acids, polypeptides, DNA and RNA. Offered by: Chemistry Fall Prerequisites: CHEM 222, or permission of the instructor. Terms Fall 2024 Instructors Masad J Damha	Introductory Organic Chemistry 3	3
MATH 222 Calculus 3 3 Credits Offered in the: Fall Winter Summer Mathematics & Statistics (Sci): Taylor series, Taylor's theorem in one and several variables. Review of vector geometry. Partial differentiation, directional derivative. Extreme of functions of 2 or 3 variables. Parametric curves and arc length. Polar and spherical coordinates. Multiple integrals. Offered by: Mathematics and Statistics Prerequisite: MATH 141. Familiarity with vector geometry or Corequisite: MATH 133 Restriction: Not open to students who have taken MATH 150, MATH 151 or MATH 262. Terms Fall 2024 Winter 2025 Instructors Brent Pym, Damien Tageddine	Calculus 3	3
MATH 315 Ordinary Differential Eqns 3 Credits Offered in the: Fall Winter Summer Mathematics & Statistics (Sci): First order ordinary differential equations including elementary numerical methods. Linear differential equations. Laplace transforms. Series solutions. Offered by: Mathematics and Statistics Prerequisite: MATH 222. Corequisite: MATH 133. Restriction: Not open to students who have taken or are taking MATH 325. Terms Fall 2024 Winter 2025 Instructors Courtney Paquette Niky Kamran or BIOL 309 Mathematical Models in Biology 3 Credits Offered in the: Fall Winter Summer Biology (Sci): Application of finite difference and differential equations to problems in cell and developmental biology, ecology and physiology. Qualitative, quantitative and graphical techniques are used to analyze mathematical models and to compare theoretical predictions with experimental data. Offered by: Biology Fall 3 hours lecture Prerequisites:BIOL 200, BIOL 201 (or ANAT 212/BIOC 212); or BIOL 219 Terms Fall 2024 Instructors Gil Bub, Frederic Guichard	Ordinary Differential Equations Mathematical Models in Biology	3 3
MIMM 323 Microbial Physiology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): An introduction to the composition and structure of microbial cells, the biochemical activities associated with cellular metabolism and how these activities are regulated and coordinated. The course will have a molecular and genetic approach to the study of microbial physiology. Offered by: Microbiology & Immunology Fall 3 hours of lecture Prerequisite: MIMM 211 Terms Fall 2024 Instructors Gregory T Marczynski	Microbial Physiology	3
MIMM 324 Fundamental Virology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): A study of the fundamental properties of viruses and their interactions with host cells. Bacteriophages, DNA- and RNA-containing animal viruses, and retroviruses are covered. Emphasis will be on phenomena occurring at the molecular level and on the regulated control of gene expression in virus-infected cells. Offered by: Microbiology & Immunology Fall 3 hours of lecture Prerequisites: MIMM 211, BIOL 200, BIOL 201 or BIOC 212 Terms Fall 2024 Instructors Jose Guerreiro Teodoro, Chen Liang, George Kukolj, Dalius J Briedis, Andrew J Mouland, Jacques Archambault, Qian Liu, Leo Liu	Fundamental Virology	3
PATH 300 Human Disease 3 Credits Offered in the: Fall Winter Summer Pathology: Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder. Offered by: Pathology Winter Prerequisites: BIOL 200, BIOL 201 or BIOC 212, PHGY 209. Pre-/co-requisite: PHGY 210 Terms Winter 2025 Instructors Edith Zorychta	Human Disease	3
PHAR 300 Drug Action 3 Credits Offered in the: Fall Winter Summer Pharmacology and Therapeutics: Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects. Offered by: Pharmacology and Therapeutics Fall Prerequisites: BIOL 200, PHGY 209, PHGY 210 and one of BIOL 201 or ANAT/BIOC 212 or permission of instructor. Terms Fall 2024 Instructors Edith Zorychta, Ajitha Thanabalasuriar, Daniel Bernard	Drug Action	3
PHAR 301 Drugs and Disease 3 Credits Offered in the: Fall Winter Summer Pharmacology and Therapeutics: This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America. Offered by: Pharmacology and Therapeutics Winter Prerequisite: PHAR 300 Terms Winter 2025 Instructors Bastien Castagner	Drugs and Disease	3
PHAR 303 Principles of Toxicology 3 Credits Offered in the: Fall Winter Summer Pharmacology and Therapeutics: Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth. Offered by: Pharmacology and Therapeutics Winter Prerequisites: BIOL 200, BIOL 201 or BIOC 212, PHGY 209 and PHGY 210 Terms Winter 2025 Instructors Maureen H McKeague	Principles of Toxicology	3
PHGY 311 Channels, Synapses & Hormones 3 Credits Offered in the: Fall Winter Summer Physiology: In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system. Offered by: Physiology Fall 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term Prerequisite: PHGY 209 or permission of the instructor. Terms Fall 2024 Instructors Ellis Cooper, Per Jesper Sjostrom, Arjun Krishnaswamy, Reza Sharif Naeini	Channels, Synapses & Hormones	3
PHGY 312 Resp.,Renal,&Cardio Physiology 3 Credits Offered in the: Fall Winter Summer Physiology: In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level. Offered by: Physiology Winter 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor Terms Winter 2025 Instructors John W Hanrahan, James G Martin, Alvin Shrier, Sheldon A Magder	Respiratory, Renal & Cardiovascular Physiology	3
PHGY 313 Blood,GI,Imm.Syst.Physiol 3 Credits Offered in the: Fall Winter Summer Physiology: In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology. Offered by: Physiology Winter 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor Terms Winter 2025 Instructors Judith N Mandl, Volker Manfred Blank, Melissa A Vollrath, Jörg H Fritz, Daniela Quail	Blood, Gastrointestinal & Immune Systems Physiology	3
PHGY 314 Integrative Neuroscience 3 Credits Offered in the: Fall Winter Summer Physiology: In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours. Offered by: Physiology Fall 3 hours of lectures per week Prerequisites: PHGY 209 Terms Fall 2024 Instructors Maurice J Chacron, Christopher C Pack, Amir Shmuel, Melissa A Vollrath, Stephen Lomber, Mark Brandon, Pouya Bashivan	Integrative Neuroscience	3

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U3 Complementary Courses (9 credits)

3 credits selected from:

BIOC 503 Biochemistry of ImmuneDiseases 3 Credits Offered in the: Fall Winter Summer Biochemistry: Current selected topics in immunology. The biochemical mechanisms underlying various immuno-pathologies and the clinical significance of therapeutic interventions. Offered by: Biochemistry Winter Prerequisites: BIOC 311, BIOC 312 Terms Winter 2025 Instructors Christos M Tsoukas, Maxime Denis	Immunochemistry	3
MIMM 509 Inflammatory Processes 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers (from McGill and other universities) and students will be furthered. Offered by: Microbiology & Immunology Winter 3 hours of seminar Corequisite: PHGY 513 or MIMM 414 This course will be given in conjunction with the Division of Experimental Medicine Prerequisite: MIMM 314 Terms Winter 2025 Instructors Joyce Rauch, Giovanni (John) Di Battista	Inflammatory Processes	3
MIMM 414 Advanced Immunology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field. Offered by: Microbiology & Immunology Fall 3 hour lecture Prerequisite: MIMM 314 Terms Fall 2024 Instructors Jörg H Fritz	Advanced Immunology	3

plus 6 credits selected from:

BIOC 404 Biophysical Methods in Biochem 3 Credits Offered in the: Fall Winter Summer Biochemistry: Applications and fundamental bases of important biophysical techniques used in modern biochemistry research laboratories to isolate, characterize and determine the structure and dynamics of proteins, nucleic acids, small molecules and complexes that underlie life and disease. Offered by: Biochemistry Winter Prerequisites: CHEM 204, CHEM 214 or equivalent Terms Winter 2025 Instructors Thomas Martin Schmeing, Kalle Gehring, Adam G Hendricks, Joaquin Ortega, Alba Guarne	Biophysical Chemistry	3
BIOC 450 Protein Structure and Function 3 Credits Offered in the: Fall Winter Summer Biochemistry: Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes. Offered by: Biochemistry Fall Prerequisites: BIOC 311, BIOC 312 and/or sufficient organic chemistry. Restriction: Intended primarily for students at the U3 level Terms Fall 2024 Instructors Bhushan Nagar, Thomas Martin Schmeing, Enrico Purisima, Kalle Gehring, Christopher J von Roretz, Christopher Thibodeaux, Alba Guarne, Maria Vera Ugalde, Natalie Zeytuni	Protein Structure and Function	3
BIOC 454 Nucleic Acids 3 Credits Offered in the: Fall Winter Summer Biochemistry: RNA processing, localization and stability. RNAi mechanisms, regulation and applications. Regulation of DNA replication. Genomics: human genome sequence, regulation and organization. DNA repair mechanisms. Special topics on transgenics, genetic diseases and cancer. Offered by: Biochemistry Fall Prerequisites: BIOC 311, BIOC 312 or permission of instructor Terms Fall 2024 Instructors William Pastor, Jose Guerreiro Teodoro, Imed Eddine Gallouzi, Alain Nepveu, Josee Dostie, Thomas Duchaine, Marc R Fabian, Sidong Huang, Ian R Watson, Katie Cockburn	Nucleic Acids	3
BIOC 458 Membranes & Cellular Signaling 3 Credits Offered in the: Fall Winter Summer Biochemistry: An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death. Offered by: Biochemistry Winter Prerequisites: BIOC 212 or ANAT 212 or BIOL201, ANAT 262, one of PHGY 209 or BIOL 205; one of BIOC 312 or ANAT 365; BIOC 311 recommended Restriction: This course is also listed as ANAT 458. Not open to students who have taken or are taking ANAT 458. Terms Winter 2025 Instructors Maxime Denis, Chantal Autexier, Nathalie Lamarche, Dieter Reinhardt or ANAT 458 Membranes & Cellular Signaling 3 Credits Offered in the: Fall Winter Summer Anatomy & Cell Biology: An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death. Offered by: Anatomy and Cell Biology Winter 3 hours lectures Prerequisites: BIOC 212 or ANAT 212 or BIOL 201, ANAT 262, one of PHGY 209 or BIOL 205; one of BIOC 312 or ANAT 365; BIOC 311 recommended Restriction: This course is also listed as BIOC 458. Not open to students who are taking or who have taken BIOC 458 Terms Winter 2025 Instructors Maxime Denis, Chantal Autexier, Nathalie Lamarche, Dieter Reinhardt	Membranes and Cellular Signaling Membranes and Cellular Signaling	3 3
BIOC 503 Biochemistry of ImmuneDiseases 3 Credits Offered in the: Fall Winter Summer Biochemistry: Current selected topics in immunology. The biochemical mechanisms underlying various immuno-pathologies and the clinical significance of therapeutic interventions. Offered by: Biochemistry Winter Prerequisites: BIOC 311, BIOC 312 Terms Winter 2025 Instructors Christos M Tsoukas, Maxime Denis	Immunochemistry	3
BIOL 520 Gene Activity in Development 3 Credits Offered in the: Fall Winter Summer Biology (Sci): An analysis of the role and regulation of gene expression in several models of eukaryotic development. The emphasis will be on critical evaluation of recent literature concerned with molecular or genetic approaches to the problems of cellular differentiation and determination. Recent research reports will be discussed in conferences and analyzed in written critiques. Offered by: Biology Winter 3 hours lecture and discussion Prerequisites: BIOL 300 and BIOL 303 or permission Terms This course is not scheduled for the 2024 academic year Instructors There are no professors associated with this course for the 2024 academic year	Gene Activity in Development	3
EXMD 504 Biology of Cancer 3 Credits Offered in the: Fall Winter Summer Experimental Medicine: An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy. Offered by: Medicine Fall Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only Terms Fall 2024 Instructors Livia Garzia, Jose Guerreiro Teodoro, Phil Gold, Penina Brodt, Patricia N Tonin, Swneke D Bailey, Jerome Fortin, Talía Malagón, Sungmi Jung, David Labbé	Biology of Cancer	3
MIMM 413 Parasitology 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): A study of the biology, immunological aspects of host-parasite interactions, pathogenicity, epidemiology and molecular biological aspects of selected parasites of medical importance. Laboratory will consist of a lecture on techniques, demonstrations and practical work. Offered by: Microbiology & Immunology Winter Prerequisite: MIMM 314 or equivalent - ANAT 261 is strongly recommended Terms Winter 2025 Instructors Greg J Matlashewski, Momar Ndao	Parasitology	3
MIMM 465 Bacterial Pathogenesis 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): Familiarizes students with key principles and recent advances in our understanding of the strategies that bacteria use to infect and cause disease, as well as the approaches used in the prevention and treatment of bacterial infections. Offered by: Microbiology & Immunology Fall 3 hours of lecture Prerequisites: MIMM 211, MIMM 314, MIMM 323, or the permission of the instructor Terms Fall 2024 Instructors Michael Reed, Dao Nguyen, Marcel A Behr, Maxime Denis, Samantha Gruenheid, Frédéric J Veyrier, Jennifer Ronholm, Corinne Maurice, Andréanne Lupien	Bacterial Pathogenesis	3
MIMM 466 Viral Pathogenesis 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): A study of the biological and molecular aspects of viral pathogenesis with emphasis on the human pathogenic viruses including the retroviruses HIV and HTLV-1; herpes viruses; papilloma viruses; hepatitis viruses; and new emerging human viral diseases. These viruses will be discussed in terms of virus multiplication, gene expression virus-induced cytopathic effects and host immune response to infection. Offered by: Microbiology & Immunology Winter 3 hours of lecture Prerequisites: MIMM 211, MIMM 324, MIMM 314 Terms Winter 2025 Instructors Chen Liang	Viral Pathogenesis	3
MIMM 509 Inflammatory Processes 3 Credits Offered in the: Fall Winter Summer Microbiology and Immun (Sci): This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers (from McGill and other universities) and students will be furthered. Offered by: Microbiology & Immunology Winter 3 hours of seminar Corequisite: PHGY 513 or MIMM 414 This course will be given in conjunction with the Division of Experimental Medicine Prerequisite: MIMM 314 Terms Winter 2025 Instructors Joyce Rauch, Giovanni (John) Di Battista	Inflammatory Processes	3
PHAR 503 Drug Discovery & Development 1 3 Credits Offered in the: Fall Winter Summer Pharmacology and Therapeutics: Chemistry, mechanisms of action, and steps in drug discovery and development. Offered by: Pharmacology and Therapeutics Fall Prerequisites: PHAR 301 or PHAR 303; or permission of instructor Terms Fall 2024 Instructors Lisa Munter, Reza Sharif Naeini, Karen Meerovitch, Albert M Berghuis, Vincent Mooser	Drug Design and Development 1	3
PHAR 504 Drug Discovery & Development 2 3 Credits Offered in the: Fall Winter Summer Pharmacology and Therapeutics: Nobel Prize-winning discoveries as a basis for drug development. Offered by: Pharmacology and Therapeutics Winter Prerequisites: PHAR 301 or PHAR 303; or permission of instructor Restriction: U3 and graduate students. Students can register only with permission of coordinators. Terms Winter 2025 Instructors Gerhard Multhaup	Drug Design and Development 2	3
PHGY 488 Stem Cell Biology 3 Credits Offered in the: Fall Winter Summer Physiology: The main concepts in stem cell biology: embryonic stem cells, induced pluripotent stem cells, cancer stem cells, stem cells populations of many adult tissues, applications of stem cell biology and ethical issues surrounding stem cell use in research and medicine. The major experimental methods and laboratory techniques in stem cell biology. Offered by: Physiology Prerequisite(s): PHGY 313 or by permission of instructor. Restriction(s): Registration is on a first-come, first-served basis. Restriction(s): Not open to students who are taking or have taken ANAT 416. Critical reading of peer-reviewed journal papers, practice in oral presentations of scientific material and participation in group discussions. Terms Fall 2024 Instructors Anastasia Nijnik, Natasha Chang, Carl P Ernst, Alexander Gregorieff, Nicoletta Eliopoulos, Anie Philip, Stefano Stifani, Brenden N Moeun, Kolja Eppert, William Pastor	Stem Cell Biology	3
PHGY 531 Topics in Applied Immunology 3 Credits Offered in the: Fall Winter Summer Physiology: Seminar format course in which experts in immunologic mechanisms of resistance against a variety of infectious diseases, including AIDS, malaria, and tuberculosis oversee student moderators in their presentation of recent scientific literature in the field. Offered by: Physiology Winter Restriction: Permission of the instructor. U3 InterDept. Honours Immunology students and graduate students with strong immunology background i.e. PHGY 513 and BIOC 503 Terms Fall 2024 Instructors Judith N Mandl, Paul Clarke, Irah King, Heather Melichar, Pouya Bashivan	Topics in Applied Immunology	3
PHGY 552 Cellular&Molecular Physiology 3 Credits Offered in the: Fall Winter Summer Physiology: Discussions of recent significant advances in our understanding of the gene products involved in diverse cellular signalling pathways. Topics will include cell-surface hormone receptors, nuclear steroid hormone receptors, and ion channels and transporters. Students will present and critically evaluate experimental approaches, results and interpretations of selected research publications. Offered by: Physiology Winter 1 hour lecture, 2 hours seminar weekly Prerequisite: PHGY 311 Preference will be given to Physiology Honours and Graduate students Terms Winter 2025 Instructors John Orlowski, John H White, Ursula Stochaj, Daniel Bernard	Cellular and Molecular Physiology	3