Dr. Eva Andermann and her collaborators investigate genetic factors in epilepsy and in epilepsy syndromes, and also examine memory and attention in epilepsy patients and their relatives. With the help of Dr. François Dubeau, Dr. Frederick Andermann, and Dr. Donatella Tampieri, she plans to conduct a major genetic study of tuberous sclerosis mutations. She will also examine corticoid displasias to determine whether they could result from mutations of the tuberous sclerosis genes. She will try to discover the genes involved in various neuronal migration disorders and in Batten disease (neuronal ceroid lipfuceinoses). Dr. Andermann provides genetic counselling to families with epileptic disorders, and has studied teratogenic effects of anti-epileptic drugs, work showing that folate supplements given before pregnancy help to prevent birth defects. With Dr. Gabriel Leonard she is studying the neuro-psychological development of school-age children of epileptic mothers.
Lopes-Cendes I, Scheffer IE, Berkovic SF, Rousseau M, Andermann E, Rouleau GA. A new locus for generalized epilepsy with febrile seizures plus maps to chromosome 2. Am J Hum Genet. 2000 Feb;66(2):698-701. Link to Article
Gambardella A, Messina D, Le Piane E, Oliveri RL, Annesi G, Zappia M, Andermann E, Quattrone A, Aguglia U. Familial temporal lobe epilepsy autosomal dominant inheritance in a large pedigree from southern Italy. Epilepsy Res. 2000 Feb;38(2-3):127-32. Link to Article
Xiong L, Labuda M, Li DS, Hudson TJ, Desbiens R, Patry G, Verret S, Langevin P, Mercho S, Seni MH, Scheffer I, Dubeau F, Berkovic SF, Andermann F, Andermann E, Pandolfo M. Mapping of a gene determining familial partial epilepsy with variable foci to chromosome 22q11-q12. Am J Hum Genet. 1999 Dec;65(6):1698-710. Link to Article
Guerrini R, Andermann E, Avoli M, Dobyns WB. Cortical dysplasias, genetics, and epileptogenesis. Adv Neurol. 1999;79:95-121. Review.
Andermann F, Andermann E, Ptito A, Fontaine S, Joubert M. History of Joubert syndrome and a 30-year follow-up of the original proband. J Child Neurol. 1999 Sep;14(9):565-9. Link to Article