Sam Audrain
Sam Audrain is studying how the brain forms long-term memories. Her lab designs experiments that leverage diverse approaches to understand the neural basis of memory, including behavioural manipulations in populations with healthy versus dysfunctional memory, polysomnography, and cutting-edge fMRI approaches at 3 and 7 Tesla. Her work focuses on how new memory traces are strengthened in the brain over time for long-term storage, and how this process fails in populations who show pathological forgetting. She is particularly interested in memory in patients with temporal lobe epilepsy, and additionally researches methods of predicting cognitive decline after surgical intervention in these patients.
Audrain, S., Wennberg, R., Tarazi, A., McAndrews, M.P. (2024). Slow wave sleep is associated with forgetting in patients with temporal lobe epilepsy. Epilepsy & Behavior. 158(2024): 109931. DOI: 10.1016/j.yebeh.2024.109931
Audrain, S., Barnett, A., Mouseli, P., & McAndrews, M. P.(2023). Leveraging the resting brain to predict memory decline after temporal lobectomy. Epilepsia. 64(11), 1–12. https://doi.org/10.1111/epi.17767
Audrain, S., & McAndrews, M. P. (2022). Schemas provide a scaffold for neocortical integration of new memories over time. Nature Communications.13(5795), 1–16. DOI: https://doi.org/10.1038/s41467-022-33517-0
Audrain, S., Gilmore, A. W., Wilson, J. M., Schacter, D. L., & Martin, A. (2022). A role for the anterior hippocampus in autobiographical memory construction regardless of temporal distance. Journal of Neuroscience. 42(33), 6445–6452. DOI: https://doi.org/10.1523/JNEUROSCI.0832-22.2022
Audrain, S., & McAndrews, M. P. (2019). Cognitive and functional correlates of accelerated long-term forgetting in temporal lobe epilepsy. Cortex. 110, 101–114. DOI: https://doi.org/10.1016/j.cortex.2018.03.022
