Updated: Sun, 10/06/2024 - 10:30

From Saturday, Oct. 5 through Monday, Oct. 7, the Downtown and Macdonald Campuses will be open only to McGill students, employees and essential visitors. Many classes will be held online. Remote work required where possible. See Campus Public Safety website for details.

Du samedi 5 octobre au lundi 7 octobre, le campus du centre-ville et le campus Macdonald ne seront accessibles qu’aux étudiants et aux membres du personnel de l’Université McGill, ainsi qu’aux visiteurs essentiels. De nombreux cours auront lieu en ligne. Le personnel devra travailler à distance, si possible. Voir le site Web de la Direction de la protection et de la prévention pour plus de détails.

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John Hanrahan

Academic title(s): 

Professor, Department of Physiology

John Hanrahan
Contact Information
Address: 

Department of Physiology
McGill University
McIntyre Medical Sciences Building,
Room 1013
3655 Promenade Sir William Osler
Montréal, Québec H3G 1Y6

Email address: 
john.hanrahan [at] mcgill.ca
Phone: 
(514) 398-8320 (office)
(514) 398-4323 (laboratory)
Department: 
Physiology
Area(s): 
Cell and Molecular Biology
Degree(s): 

BSc(Hon), Dalhousie; PhD, UBC; Postdoc, Yale 

Current research: 

Our main goal is to understand epithelial chloride transport at the molecular level.  Most of our effort focuses on CFTR (cystic fibrosis transmembrane conductance regulator), a low-conductance channel which mediates cAMP-stimulated chloride and bicarbonate secretion and is defective in the disease cystic fibrosis.  We use site-directed mutagenesis, electrophysiological and imaging methods to study the structure and function of CFTR in heterologous expression systems, cell lines, and primary epithelial cell cultures.  A recent emphasis has been the development of F508del-CFTR correctors for the treatment of CF. Other projects investigate the role of CFTR in mucus production and in chronic obstructive pulmonary disease. 

Link(s): 
Lab Website
Selected publications: 

PubMed Listing

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