Collage of microbes, bacteria, disease

Tracking progress along the WHO Neglected Tropical Diseases Road Map to 2030: A guide to the Gap Assessment Tool (GAT) and results from the 2023-2024 assessment

Tue, 07/01/2025 - 06:00
The monitoring and evaluation (M&E) framework for the World Health Organization (WHO) Neglected Tropical Diseases (NTD) road map includes both quantitative and qualitative assessments of progress at key timepoints up to 2030. These assessments provide critical information to improve programmatic action and identify immediate research needs. Quantitative assessments process multi-sourced data on a predefined number of global indicators. Qualitative assessments are based on results obtained from...

Resurgence of chikungunya in the Indian Ocean Region in 2024-2025

Fri, 06/27/2025 - 06:00
In the wake of a large outbreak in Reunion and Mayotte the GeoSentinel network has been signalling chikungunya cases among returning travellers acquired in multiple African and Asian countries between August 1st 2024 and June 10th 2025. These surveillance data suggest a resurgence of chikungunya in the Indian Ocean Region.

Clinical Practice Guideline-Supported Administration of Monoclonal Antibody Therapy for High-Risk Patients with COVID-19: Experience of a Quaternary Care Centre

Wed, 06/25/2025 - 06:00
CONCLUSION: CPG-supported mAb administration for management of COVID-19 in high-risk patients was associated with favourable clinical outcomes and may be a useful model to guide future therapies.

Antibiotic synergy against <em>Staphylococcus aureus</em>: a systematic review and meta-analysis

Tue, 06/17/2025 - 06:00
Antimicrobial combinations have been extensively evaluated in vitro to identify synergistic combinations for clinical use. Despite the available literature, no studies comprehensively summarize the findings for antimicrobial combinations against Staphylococcus aureus. We performed a systematic review to identify synergistic combinations that may be beneficial for clinical use against S. aureus. The PubMed, Cochrane, and Web of Science databases were queried from inception to February 2024 for...

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