Biological Osteopontin-based dental coating to fill tooth cracks

Invention 2019-073

Biological Osteopontin-based dental coating to fill tooth cracks

A biologic dental coating that prevents tooth crack propagation made of the bone and tooth protein Osteopontin was developed at McGill University.

Market Need

Over time, repeated physical pressure on teeth creates micro-cracks that could eventually lead to tooth fracture. These fractures are repaired with porcelain or ceramic crowns, but they often need to be replaced since they are not as tough as natural teeth. The addition of metal could be used to strengthen the crowns, but this can lead to visible dark spots in the gums or inflammation. If the failed crowns lead to deeper cracks, tooth replacement or further surgery could be required.

Technology Summary

Composed of the biological bone and tooth protein Osteopontin with the addition of a cross-linker, this invention provides a new method of filling existing cracks and preventing crack propagation. Since this technology is biologically based, this dental coating could potentially even heal pre-existing tooth cracks with mineralization. The time of administration will also be beneficial to dentists as the application requires only a short time (in the range of tens of minutes).

Advantages

• Composed of the tooth protein Osteopontin and cross-linkers, this invention provides a strong biological alternative to traditional crowns
• Quick fabrication and application of the coating for tooth surfaces

Patent Status

Filed US