1,2-Oxy-aminoarenes are omnipresent in biologically active molecules and advanced materials, but current syntheses are often atom and step inefficient, and can require highly optimized and expensive catalysts. Recent work, conducted by graduate student Kenn Esguerra and postdoc Wenbo Xu in the Lumb Group, has made important strides towards improving the efficiency of 1,2-oxy-amioarene synthesis by interfacing two unrelated, but complementary, biosynthetic processes.
At the University of New Brunswick this morning, The Honourable Kirsty Duncan, Minister of Science, announced $51,968,051 for 223 projects at 39 universities across the country, including over $4.5 million across 14 projects at McGill, through the Canada Foundation for Innovation’s (CFI) John R. Evans Leaders Fund. The Fund was established to help universities like McGill innovate, as well as to attract and retain top research talent, by giving them access to cutting-edge research equipment, laboratories and tools.
Xijie Dai, Haining Wang and C.J. Li have recently demonstrated that carbonyl derivatives could be used in a similar fashion to Grignard reagents using a smart Umpolung strategy and thus replaced organometallic-based reagents for nucleophilic carbonyl addition reactions for alcohol synthesis.
For the second year in a row, students from the Green Chemistry course (CHEM 462) are releasing their journal issue, published online as The McGill Green Chemistry Journal. This volume gathers the reviews written by students who took the course. Students used peer evaluation, similar to the standard in scientific publication as a means to raise the quality of all the papers submitted.
The Sir William C. Macdonald Chair in Chemistry was established in 1901 and is one of the oldest Named Chairs at the University.
Dima has a significant international reputation that was recently validated in the Full Professor promotion process, and are one of the world’s most creative “designers” and makers of novel materials.
Graduate student Bryan Lee from Dr. Ariya group has submitted a video for the 2017 NSERC Science, Action! competition. His video is titled “Mercury on the Move”, which briefly speaks on the impact of mercury pollution in the environment to the public. His video is live on YouTube now, which can be found here.
It is with great sadness that we announce the untimely passing of Emeritus Professor Donald Patterson at age 89. Donald Patterson was born on October 13, 1927, in Montreal where he excelled at school, first at Selwyn House and then at Westmount High. In 1944, he placed first in the province in the Quebec high school final exams. He went on to study Mathematics and Physics at McGill University (B.Sc. ’48 ; M.Sc. ’50), and then chemistry for his PhD at the University of Bristol, England (1950-1953).
Dr. Cristina Mottillo is the recipient of the prestigious 2017 CCUCC Chemistry Doctoral Award from the Canadian Institute of Chemistry (CIC). The Award, sponsored by the Canadian Council of University Chemistry Chairs (CCUCC), recognizes a recent Ph.D. graduate for their outstanding achievement and potential in research. Cristina performed her Ph.D.
The Natural Sciences and Engineering Research Council of Canada has awarded an E.W.R Steacie Memorial Fellowship to Prof. Tomislav Friščić, to support his work in an innovative branch of chemistry that aims to develop environmentally friendly alternatives to solvent-based chemical processes.
NSERC awards up to six of these two-year, $250,000 fellowships annually to enhance the career development of outstanding and highly promising scientists and engineers.
Human farnesyl pyrophosphate synthase (hFPPS) plays a key role in the prenylation of small GTPases, such as RAS and RAP 1A, which are intimately involved in oncogenesis. An allosteric pocket of the enzyme has been of particular interest as a therapeutic target, however, its natural biological function has been (until now) unknown. The teams of Berghuis (Biochemistry) and Tsantrizos (Chemistry) have just reported that the catalytic product of hFPPS, farnesyl pyrophosphate (FPP), bind to this pocket and locks the enzyme in a conformationally inactive state.
Prof. Tony Mittermaier was awarded a CFI-John R. Evans Leaders Fund to acquire a 800 MHz nuclear magnetic resonance (NMR) magnet. Most human diseases are caused by malfunctions in the fundamental molecules of life: proteins, DNA, and RNA. Studying the structure and flexibility of the molecules at the atomic level therefore helps us to understand diseases and find cures, much in the same way that the blueprint of an engine can help us to fix it when it is broken.
ECS recently announced the appointment of Janine Mauzeroll to the position of Technical Editor for the Organic & Bioelectrochemistry area for the Journal of The Electrochemical Society (JES). Read more about Dr. Mauzeroll’s research areas and her plans for growing this area of JES.
On December 2016, Prof. Ashok Kakkar was promoted full professor.