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How Salmonella tackles cellular defense mechanisms

Researchers uncover new protein that plays key role in bacterial infections

Bacterial infections represent a major public health concern, accounting for over 300 million foodborne illnesses and 60% of related fatalities globally. Salmonella alone is responsible for approximately 93.8 million illnesses and 155,000 deaths annually. Combined with the emergence of antibiotic-resistant Salmonella strains, it is critical that researchers improve our understanding of the molecular details governing bacterial infections.

Classified as: complex traits, salmonella
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Published on: 9 Sep 2019

Early life factors connected to suicide risk later in life

Researchers have long been interested in the question of whether a correlation exists between one’s early-life environment and suicide rates, with studies on the topic dating back to the 1980s. However, these studies have focused on individual countries or on only one or few risk factors. As a result, the lack of any meta-analysis of the data has made it difficult to draw any coherent conclusions.

Classified as: Douglas Mental Health University Institute, Psychiatry, suicide
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Published on: 9 Sep 2019

Amal Seffouh, a Postdoctoral Fellow in the Ortega lab, publishes her most recent work about the role of RbgA in the maturation of the 50S ribosomal subunit

Amal Seffouh, a Postdoctoral Fellow in the Ortega lab, publishes her most recent work about the role of RbgA in the maturation of the 50S ribosomal subunit.

 

Click here to read the paper.

 

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Published on: 9 Sep 2019

A new study shows that the hippocampus retains traces of negative and stressful experiences which are linked to depressive behaviours

Depression can be associated with behaviours such as social avoidance, that is, the refusal to interact with others for fear of being judged or criticized. Physicians and other mental health workers have noted that patients with depressive disorders exhibit cognitive symptoms, especially with regard to memory.

Classified as: hippocampus, McGill Department of Psychiatry, memory
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Published on: 13 Aug 2019

Two McGill professors lead new Stand Up to Cancer Canada Metastatic Breast Cancer Dream Team

Marc Miller, Member of Parliament (Ville-Marie–Le Sud-Ouest–Île-des-Sœurs, Quebec) and Parliamentary Secretary to the Minister of Crown-Indigenous Relations, on behalf of the Honourable Ginette Petitpas Taylor, Minister of Health, announced today at McGill an investment of up to $6 million for a scientific task force of top researchers to develop new and improved approaches to cancer treatment and care. The funding will be distributed over four years to the new pan-Canadian program, the Stand Up to Cancer (SU2C) Canada Metastatic Breast Cancer Dream Team.

Classified as: stand up to cancer, Nahum Sonenberg, Michael Pollak, faculty of medicine, Oncology, breast cancer
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Published on: 12 Aug 2019

Surgery simulators are key to assessment of trainees

AI and virtual reality can determine neurosurgeon expertise with 90% accuracy

Machine learning-guided virtual reality simulators can help neurosurgeons develop the skills they need before they step in the operating room, according to a new study.

Classified as: MNI, rolando del maestro, neurosurgical stimulation, Artificial intelligence, Montreal Neurological Institute and Hospital (The Neuro), National Research Council of Canada, NeuroVR
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Published on: 2 Aug 2019

Study finds Nunavik Inuit are genetically unique

Variants found in this population may predispose to brain aneurysm

A new study has found that an Inuit population in Canada’s Arctic are genetically distinct from any known group, and certain genetic variants are correlated with brain aneurysm.

Classified as: aneurysm, Guy Rouleau, Sirui Zhou, Inuit, Canada, Nunavik, genetics
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Published on: 23 Jul 2019

Research team receives $6M to find new ways to treat metastatic breast cancer

Source: Terry Fox Research Institute

What is the best way to starve cancer cells? What role does obesity play in metastatic breast cancer and how does it affect the tumour microenvironment? Might combining a chemotherapeutic agent with a drug now used to treat diabetes be part of an effective therapy for metastatic breast cancer?

Classified as: breast cancer, Goodman Cancer Research Centre
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Published on: 4 Jul 2019

Aida Razi’s last PhD thesis chapter now published online in the Nucleic Acids Research journal. This publication features the first cryo-EM structures obtained by the Ortega lab in the Titan Krios microscope at FEMR-McGill

Aida Razi’s last PhD thesis chapter now published online in the Nucleic Acids Research journal. This publication features the first cryo-EM structures obtained by the Ortega lab in the Titan Krios microscope at FEMR-McGill.

 

Read the paper at https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz571/5527280?searchresult=1

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Published on: 4 Jul 2019

Researchers unlock mysteries of complex microRNA oncogenes

New research led by McGill’s Goodman Cancer Research Centre improves our understanding of microRNAs

 

Classified as: cancer research, Goodman Cancer Research Centre, MicroRNA
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Published on: 27 Jun 2019

McGill researchers reveal how protein mutation is involved in rare brain development disorder

Discovery could provide clues to potential therapies

Rearing its head in infancy, Christianson Syndrome is a rare disorder whose symptoms include intellectual disability, seizures and difficulty standing or walking. Although it is becoming increasingly diagnosed, with little being known about the neural mechanism behind the disease, therapeutic options for patients remain limited.

Classified as: Brain@McGill, neuroscience
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Published on: 27 Jun 2019

Dr Natalie Dayan named Quebec's First Research Chair in Women's Heart Health!

Dr Natalie Dayan was named Quebec’s first Research Chair in Women’s Heart Health on 18 June 2019!

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Published on: 19 Jun 2019

Dr Isabelle Malhamé joins the Division of General Internal Medicine

We are pleased to announce the appointment of Dr. Isabelle Malhamé to the Division of General Internal Medicine as of June 1, 2019. Dr Malhamé has been appointed to the Attending Staff of the MUHC Department of Medicine, Division of General Internal Medicine, and as an Assistant Professor in the McGill University Department of Medicine. 

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Published on: 19 Jun 2019

Inducing seizures to stop seizures

Cortical stimulation-induced seizures have the potential to guide epilepsy surgery, significantly reducing hospital stays

Surgery is the only way to stop seizures in 30 per cent of patients with focal drug-resistant epilepsy. A new study finds that inducing seizures before surgery may be a convenient and cost-effective way to determine the brain region where seizures are coming from.

Classified as: epilepsy, Birgit Frauscher, Francois Dubeau, Jean Gotman, Jeffrey Hall, Cortical stimulation
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Published on: 11 Jun 2019

Alan Evans honoured for his lifetime contribution to the field of neuroimaging

The Organization for Human Brain Mapping, the largest international scientific society for neuroimaging-based brain research, has honoured Prof. Alan C. Evans with its Glass Brain Award

The award, presented to Evans at the 2019 OHBM congress in Rome, recognizes lifetime achievement in the use of brain mapping to make significant discoveries about the human brain.

Classified as: MNI, Alan Evans, HBHL, neuroscience, neuroinformatics, neuroimaging
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Published on: 9 Jun 2019

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