Willemiek obtained her medical degree at the University of Utrecht in the Netherlands in November 2015.
Through her research thesis project she got interested in epilepsy and epileptic source localization using high frequency oscillations (HFOs) and functional connectivity.
She is now pursuing a PhD at the University Medical Center in Utrecht, the Netherlands, focusing on HFOs and functional connectivity to improve localization of the epileptogenic tissue for surgery.
In October 2019 she joined the Montreal Neurological Institute for a six month project in which she will study the localizing value of HFOs after correction for their physiological rates.
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Email: W.J.E.Zweiphenning [at] umcutrecht.nl / wilhelmina.zweiphenning [at] mail.mcgill.ca Address: Montreal Neurological Institute 3801 University Street room 009e H3A 2B4 Montreal Phone number: Office: (514) 398 6644, ext 00445 |
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Publications:
Zijlmans M, Zweiphenning W, van Klink N. Changing concepts in presurgical assessment for epilepsy surgery. Nat Rev Neur. 2019 Jul 24; 15: 594-606. Doi:10.1038/s41582-019-0224-y.
Zweiphenning W, Keijzer H, Van Diessen E, Van 't Klooster M, Van Klink N, Leijten F, Van Rijen P, Van Putten M, Braun K, Zijlmans M. Increased Gamma and Decreased Fast Ripple Connections of the Epileptogenic Tissue: a High Frequency Directed Network Approach. Epilepsia. 2019 Jul 2;00: 1-13. Doi:10.1111/ep.16296.
Van 't Klooster M, Van Klink N, Zweiphenning W, Leijten F, Zelmann R, Ferrier C, Van Rijen P, Otte W, Braun K, Huiskamp G, Zijlmans M. Tailoring epilepsy surgery with fast ripples in the intra-operative ECoG. Ann Neurol. 2017 Apr 5. Doi:10.1002/ana.24928.
Zweiphenning WJ, van ‘t Klooster MA, van Diessen E, van Klink NE, Huiskamp GJ, Gebbink TA, Leijten FS, Gosselaar PH, Otte WM, Stam CJ, Braun KP, Zijlmans GJ. High frequency oscillations and high frequency functional network characteristics in the intraoperative electrocorticogram in epilepsy. Neuroimage Clin. 2016 Nov 4; 12:928-939.
Fedele T, van ‘t Klooster M, Burnos S, Zweiphenning W, van Klink N, Leijten F, Zijlmans M, Sarnthein J. Automatic detection of high frequency oscillations during epilepsy surgery predicts seizure outcome. Clin Neurophysiol. 2016 Sep; 127(9):3066-74. oi:10.1016/j.clinph.2016.06.009.
Zweiphenning WJ*, van Diessen E*, Jansen FE, Stam CJ, Braun KP, Otte WM. Brain Network Organization in Focal Epilepsy: A Systematic Review and Meta-Analysis. PLoS One. 2014 Dec 10;9(12):e114606. Doi: 10.1371/journal.pone.0114606.